Health risks associated with milk contamination can take many forms. There is currently little data on the trends in microbial contamination and the mapping of its distribution. This study aims to map the spread of microbial contamination in cattle milk throughout ASEAN and assess trends in this area. A database originating from Scopus is collected using Boolean operators. This research used 19,967 papers as references with topics or themes of bacteria, milk, microbes, and antibiotics with loci in the ASEAN region. The analysis results show that 2021 is the peak of article production with 49 articles, followed by 2022 with 40 articles. The most productive institution is Khon Kaen University. Key research topics include antimicrobial resistance, lactic acid bacteria, bovine health issues, and fermentation in milk production. Research on antimicrobial resistance, the use of lactic acid bacteria in dairy products, cow health, and the milk fermentation process needs to be explored further. Collaboration between countries, especially Thailand and Malaysia, must also be improved to produce higher-quality research.